منابع مشابه
Studies on free radicals, antioxidants, and co-factors
The interplay between free radicals, antioxidants, and co-factors is important in maintaining health, aging and age-related diseases. Free radicals induce oxidative stress, which is balanced by the body's endogenous antioxidant systems with an input from co-factors, and by the ingestion of exogenous antioxidants. If the generation of free radicals exceeds the protective effects of antioxidants,...
متن کاملScavenging Effects of Dexrazoxane on Free Radicals
Dexrazoxane (ICRF-187) has been clinically used to reduce doxorubicin-induced cardiotoxicity for more than 20 years. It has been proposed that dexrazoxane may act through its rings-opened hydrolysis product ADR-925, which can either remove iron from the iron-doxorubicin complex or bind to free iron, thus preventing iron-based oxygen radical formation. However, it is not known whether the antiox...
متن کاملEffects of free radicals on coronary artery.
Coronary arteries supply blood to the heart and hence the control of coronary tone is pivotal to human survival. Reactive oxygen species (ROS) in specified amounts play an important role in normal metabolic and signalling processes. However, excess ROS can cause severe cardiovascular damage. For example, NO is produced by endothelium as a signal for relaxation. However, in an inflammatory respo...
متن کاملA Primer on Free Radicals and Antioxidants
Free radicals inflict damage upon other compounds by stealing electrons from them, which initiates bouts of inflammation that can lead to scar tissue formation. For example, if enough free radicals steal electrons from the inner wall of one of your blood vessels, the resulting inflammation can lead to hardening of the vessel wall, which can cause compromised blood circulation in that area of yo...
متن کاملThe Simplest Free Radicals
INTRODUCTION Every lexicographer knows that the meaning of a word is time dependent, and, in favour of the argument that it is also dependent on latitude and longitude, the perverse amonst us would cite Oscar Wilde's dictum, "England and America are two countries separated by a common language". Certainly the word radical has changed its meaning for chemits who originally thought of it as part ...
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ژورنال
عنوان ژورنال: Nature
سال: 1952
ISSN: 0028-0836,1476-4687
DOI: 10.1038/169618a0